Tze Leung Lai

My present research areas include sequential experimentation, adaptive design and control, stochastic optimization, time series analysis and forecasting, change-point detection, hidden Markov models and particle filters, empirical Bayes modeling, multivariate survival analysis, probability theory and stochastic processes, biostatistics, econometrics, quantitative finance and risk management. My methodological research in these areas has been motivated by and is closely related to my applied interests in engineering, finance, and the biomedical sciences. As director of the Financial Mathematics Program, co-director of the Biostatistics Core of the Stanford Cancer Institute, and co-director of the Center for Innovative Study Design in the Stanford School of Medicine, I am involved in multiple research projects in these fields.